Wiley Click Reactions in Organic Synthesis Srinivasan

6 Click Chemistry: Mechanistic and Synthetic Perspectives 6 Ramesh Ramapanicker and Poonam Chauhan6. 6. 7 Copper–Catalyzed Azide Alkyne Cycloaddition (CuAAC) Click Reaction 76. 8 Ruthenium–Catalyzed Azide Alkyne Cycloaddition (RuAAC) Click Reactions 77 Applications of Click Chemistry in Drug Discovery and Development 75 Balasubramanian Gopalan and Kalpattu Kuppusamy Balasubramanian7. 7 Part A: Application of Click Chemistry to Drug Discovery and Development 75

Click Chemistry

Our site uses cookies to improve your experience. You can find out more about our use of cookies in, including instructions on how to turn off cookies if you wish to do so. By continuing to browse this site you agree to us using cookies as described in. This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures. By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.

Maria Jos Ar valo, scar L pez and Maria Victoria GilFranck Amblard, Ozkan Sari, Sebastien Boucle, Ahmed Khalil and Raymond F. Schinazi We use cookies to give you the best possible experience on ResearchGate. Read our cookies policy to learn more. We ll award them after completing your purchase. You ll see how many points you ll earn before checking out.

Synthesis The click concept The Royal Society of Chemistry

At Kobo, we try to ensure that published reviews do not contain rude or profane language, spoilers, or any of our reviewer s personal information. You ve successfully reported this review. We appreciate your feedback. Previous article in issue Next article in issue Keywords Click chemistry Polysaccharide Chemical modification Hydrogel Drug delivery Olefin metathesis Choose an option to locate/access this article: Check if you have access through your login credentials or your institution. This action might not be possible to undo.

Are you sure you want to continue? In addition to carbene–promoted MCRs and frequently applied metal–catalyzed MCRs, it also covers recently developed catalytic enantioselective variants as well as MCR in drug discovery and for the synthesis of heterocyclic molecules and macrocycles. Edited by the leading experts and with a list of authors reading like a who′s who in multicomponent reaction chemistry, this is definitely a must–have for every synthetic organic chemist as well as medicinal chemists working in academia and pharmaceutical companies. Metal catalysis plays an increasingly important role in these reactions, often allowing several stereocenters to be selectively created and integrated in the target molecules.

Kobayashi and Jorgensen's handbook provides numerous examples of metal-catalyzed reactions, including [7+6], [8+7] and [9+7] cycloadditions. A large number of experimental procedures gives a concrete idea of the use of metal-catalyzed cycloaddition reactions in modern synthesis. The book is aimed at chemists in industry or academia, who want to effectively use cycloadditions in their work.